AutoGen
Microsoft's multi-agent conversation framework
Verdict
Pioneered multi-agent conversation patterns. v0.4 rewrite (AgentChat) is cleaner and more composable. Good for complex workflows needing agent-to-agent collaboration. Strong research backing.
Other AI Agents & Platforms
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OpenAI's current API for building agents — merges Chat Completions simplicity with Assistants-era tool use
- OpenAI Assistants APISuperseded
Managed agent platform with tools, files, and persistent threads — deprecated in favour of the Responses API
- Claude MCP / Tool UseProduction
Anthropic's Model Context Protocol for universal tool integration
- Microsoft Copilot StudioProduction
Enterprise agent builder with Microsoft 365 and Azure integration
- CrewAIStable
Role-based multi-agent framework with simple, intuitive API
- LangGraphStable
Stateful agent workflows as controllable graphs from LangChain