OpenAI Responses API
OpenAI's current API for building agents — merges Chat Completions simplicity with Assistants-era tool use
Verdict
OpenAI's recommended way to build agents going forward. Combines built-in tools (web search, file search, code interpreter, computer use) with a simpler, stateless-by-default request shape than the old Assistants API. This is where new integrations should start.
Other AI Agents & Platforms
- OpenAI Assistants APISuperseded
Managed agent platform with tools, files, and persistent threads — deprecated in favour of the Responses API
- Claude MCP / Tool UseProduction
Anthropic's Model Context Protocol for universal tool integration
- Microsoft Copilot StudioProduction
Enterprise agent builder with Microsoft 365 and Azure integration
- AutoGenStable
Microsoft's multi-agent conversation framework
- CrewAIStable
Role-based multi-agent framework with simple, intuitive API
- LangGraphStable
Stateful agent workflows as controllable graphs from LangChain

